The new building features novel design aspects and has received LEED Gold designation from the U.S. The foundation works began in January 2013.
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The site preparation works for the new genomic medicine facility’s construction began at the end of November 2012. The preliminary construction works, which included demolition of some structures in the 17-acre site, began in October 2012. "The genomic facility created 842 jobs during the construction phase." The research is focused on treatments for conditions such as cancer, diabetes, heart disease and Alzheimer’s disease. The facility brings together doctors, patients, scientists and industry members to indentify genetic problems and develop individualised treatments. The oval-shaped building is located adjacent to the main research building and houses an auditorium, conference rooms, media training areas and administrative offices. It houses a data processing centre, private offices and shared areas for scientists belonging to different streams. The new genomic medicine facility has flexible laboratory spaces, computational biology areas and scientific support services. It is equipped with sophisticated computing facilities and laboratories. It will provide space for 300 biomedical researchers, technicians and support staff by 2020. It is constructed in a 17-acre site belonging to the UCHC campus. The new lab facility is a four-level building with a total floor space of 183,500ft 2. "The new laboratory enables JAX to develop new medical treatments tailored to the genetic makeup of each patient."
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“I think once we have our full cohort completed we’ll be able to see markers that may be more canine specific. “We’ve already confirmed that there are similarities, from a molecular perspective, between markers for human gliomas and those for dogs,” Dr.
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The canine cohort, which according to JAX is the largest ever assembled, combines brachycephalic breeds with other breeds, such as Doberman Pinschers, Labrador, and Retrievers. Working with Texas A&M University and its network of veterinary clinics, the researchers as of November collected 180 postmortem samples from dogs with brain tumors, cancer and normal samples from 70 dogs, and cancer-only samples from another 40 dogs.
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Anderson, neurosurgeon Amy Heimberger, M.D., are conducting preclinical immunotherapy trials in dogs through a grant from the NIH’s National Cancer Institute. Anderson Cancer Center-has focused on studying the elevated risk of gliomas or glioblastomas in short-snouted or brachycephalic breeds of dogs, which include Boston terriers, Pugs, French Bulldogs, Shih-Tzus, and Pekingese.ĭr. Within JAX, the laboratory of Roel Verhaak, Ph.D.-who joined the Laboratory last year from the University of Texas M.D. Dogs appear to be ideal pets for such research, as strong similarities in the genetic aberrations and gene expression patterns of dog and human cancers have been confirmed since the sequencing of the dog genome more than a decade ago. TTCRI aims to expand the knowledge gained through human–canine comparative oncology, the branch of cancer research focused on studying naturally occurring cancer models in pets, then applying what is learned from them to human cancer R&D. This strategy is particularly useful for cancers that are rare among humans, but commonly found in certain dog breeds.” “Subsequently, identifying corresponding regions in human genomes might potentially uncover new regulatory elements that encourage these types of cancers in humans. “By studying specific dog breeds’ genomes, we can work to identify which parts of the genome differ between breeds and could contribute to cancer,” Charles Lee, Ph.D., FACMG, scientific director and professor at JAX Genomic Medicine, said in a statement.